OtherStomach cancer

Trend of geographical distribution of stomach cancer in Iran from 2004 to 2014

BMC Gastroenterol · 2022Iranian National Cancer Registry data; including 49,907 male patients (70.0%)
Moradian F, Fararouei M, Karami M, Ghelichi-Ghojogh M, Gheibi Z, Nikeghbalian Z, et al. BMC Gastroenterol. 2022. 22:4
Study type
Other
Design
Descriptive epidemiological study based on data from the Iranian National Cancer Registry (2004 to 2014)
Sample size
Iranian National Cancer Registry data; including 49,907 male patients (70.0%)
Source
BMC Gastroenterol · 2022

In plain words

Using data from Iran's national cancer registry, this research showed that stomach cancer is more common in Iran than the world average. The type and location of stomach cancer are not the same across the country's provinces, and these differences may be linked to different factors in different regions. Most patients were men, and the most common tumour sites were the cardia (the top of the stomach) and the pylorus (the outlet of the stomach). More studies are needed to understand the causes of these differences.

Key results

49,907 (70.0%)
Proportion of male patients
Patients were predominantly men
A1 (about 96.4%) and C3 (2.0%)
Most common tumour type
Significant difference in the distribution of tumour types between men and women (P < 0.001)
Significant difference
Difference in the distribution of stomach cancer types between provinces
P < 0.001
Significant difference
Difference in the distribution of tumour sites between men and women and between provinces
P < 0.001
Pylorus 28.1% and cardia 31.3%
Most common tumour sites
In the study population

Study population

Patients with stomach cancer recorded in the Iranian National Cancer Registry (INCR) during 2004 to 2014. Patients were predominantly men (49,907, 70.0%). Exact inclusion criteria are not stated in the abstract.

Endpoints

Crude and age-standardised incidence rates of stomach cancer in each province, and the frequency distribution of stomach tumour types and sites by province.

Safety and side effects

This is a descriptive epidemiological study and no treatment adverse events are reported.

Clinical significance and place in guidelines

This study is descriptive and makes no direct treatment recommendations. Its findings may be useful for health planning and for prioritising aetiological studies in the different provinces of Iran. Any use in guidelines or screening should be checked separately.

Limitations

According to the abstract, this study is descriptive and did not examine risk factors or the causes of provincial differences; the authors themselves stress the need for further studies to understand the epidemiology and aetiology. Other limitations (such as the quality and completeness of registry data) are not given in the abstract and should be checked in the full text.

This summary was prepared by the editorial team from the published paper; the original paper is the final reference. Read the original abstract on PubMed.