Evidence library

Structured summaries of the key trials and international clinical guidelines that underpin today’s cancer treatments.

659 studies129 guidelines21 areas

International clinical guidelines

Key recommendations of ESMO, NCCN, EAU and other societies.

All 129 guidelines
Clinical guideline

Advanced and metastatic prostate cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up

Ann Oncol · 2026
Clinical guideline

BCLC strategy for prognosis prediction and treatment recommendations: The 2026 update

J Hepatol · 2026
Clinical guideline

Breast Cancer, Version 4.2026, NCCN Clinical Practice Guidelines In Oncology

J Natl Compr Canc Netw · 2026
Clinical guideline

EAU Guidelines on Nonmuscle-invasive Bladder Cancer (TaT1 and CIS) - A Summary of the 2026 Guidelines Update

Eur Urol · 2026
Clinical guideline

EAU-EANM-ESTRO-ESUR-ISUP-SIOG Guidelines on Prostate Cancer—2026 Update. Part I: Screening, Diagnosis, and Local Treatment with Curative Intent

Eur Urol · 2026
Clinical guideline

EHA Guidelines on management of chronic lymphocytic leukemia and Richter transformation

HemaSphere · 2026

Latest studies

Clinical trial · Phase 3

[177Lu]Lu-PSMA-617 in patients with PSMA-positive metastatic androgen pathway modulator-naive/sensitive prostate cancer (PSMAddition): a phase 3 randomised, controlled trial

Lancet · 2026
HR 0.72Radiographic progression-free survival
Clinical trial · Phase 3

Addition of autologous stem-cell transplantation to an ibrutinib-containing first-line treatment in patients aged 18-65 years with mantle cell lymphoma (TRIANGLE): 4·5-year follow-up of a three-arm, randomised, open-label, phase 3 superiority trial of the European MCL Network

Lancet · 2026
82% vs 81%4-year FFS: A+I vs I
Clinical trial · Phase 3

Adjuvant nivolumab versus placebo for high-risk muscle-invasive urothelial carcinoma: 5-year efficacy and ctDNA results from CheckMate 274

Annals of Oncology · 2026
21.9 months (95% CI 18.8–36.9) with nivolumab vs 11.0 months (8.3–16.6) with placeboMedian DFS in all randomised patients
Clinical trial · Phase 3

Adjuvant pembrolizumab for the treatment of clear cell renal cell carcinoma: five-year results from the phase III KEYNOTE-564 study

Ann Oncol · 2026
60.9% vs 52.2%5-year disease-free survival
Clinical trial · Phase 3

Adjuvant Pembrolizumab plus Belzutifan for Renal-Cell Carcinoma

N Engl J Med · 2026
80.7% vs 73.7%24-month disease-free survival
Review article

Advances in multiple myeloma: key updates from the ASH 2025 meeting

J Hematol Oncol · 2026
Conversion from persistent MRD-positive to MRD-negative in all evaluable patientsIMMUNOPLANT (MRD-adapted consolidation in NDMM)