Other

Cancer statistics, 2026

CA A Cancer J Clinicians · 2026US population data; no specific sample size stated in the abstract
Siegel RL, Kratzer TB, Wagle NS, Sung H, Jemal A. CA A Cancer J Clinicians. 2026. 76:e70043
Study type
Other
Study name
Cancer Statistics 2026
Design
Annual statistical report based on population data (central cancer registries for incidence up to 2022 and the National Center for Health Statistics for mortality up to 2023)
Sample size
US population data; no specific sample size stated in the abstract
Source
CA A Cancer J Clinicians · 2026

In plain words

This report shows that in the United States deaths from cancer have been falling for many years and more patients are surviving. Today 70% of people are alive 5 years after a cancer diagnosis, and even in advanced cancers, such as myeloma and melanoma, survival has improved markedly. This improvement comes from less smoking, earlier diagnosis and better treatments. Even so, lung cancer is still the deadliest cancer, and access to health insurance and support for research matter for this progress to continue.

Key results

About 2,114,850 cases
New cancer cases (2026 projection, United States)
About 626,140 deaths
Cancer deaths (2026 projection, United States)
4.8 million
Deaths averted since 1991
The cancer mortality rate has fallen through 2023
70% vs 63% in the mid-1990s
5-year relative survival (all stages, diagnosed 2015–2021)
69% vs 54%
5-year relative survival (regional stage)
35% vs 17%
5-year relative survival (distant/metastatic stage)
From 32% to 62%
Myeloma
From 7% to 22%
Liver cancer
From 16% to 35%
Metastatic melanoma
From 8% to 18%
Metastatic rectal cancer
From 20% to 37%
Regional-stage lung cancer
From 2% to 10%
Metastatic lung cancer

Study population

The US population; incidence data were collected from central cancer registries (up to 2022) and mortality data from the National Center for Health Statistics (up to 2023).

Endpoints

Projected numbers of new cancer cases and cancer deaths in the United States for 2026, trends in cancer mortality rates, and 5-year relative survival by stage.

Safety and side effects

This is a statistical report and does not examine treatment adverse events.

Clinical significance and place in guidelines

This is a statistical report and makes no new treatment recommendations. According to the abstract, progress from reduced smoking, screening and early detection, and better treatments has led to lower mortality and higher survival; this finding highlights the importance of continued tobacco control policies, early detection and access to treatment. The data relate to the US population, and direct generalisation to other populations should be made with caution.

Limitations

The abstract does not mention methodological limitations. The data relate to the United States and cover incidence up to 2022 and mortality up to 2023; the 2026 figures are projections (estimates), not actual counts. Further details are available in the full text of the paper.

This summary was prepared by the editorial team from the published paper; the original paper is the final reference. Read the original abstract on PubMed.