CBTRUS Statistical Report: Primary Brain and Other Central Nervous System Tumors Diagnosed in the United States in 2017–2021
- Study type
- Other
- Study name
- CBTRUS 2017–2021
- Design
- Population-based registry epidemiological statistical report (Central Brain Tumour Registry of the United States, CBTRUS)
- Sample size
- Entire US population (population-based registry data; total number of cases not given in the abstract)
- Source
- Neuro-Oncology · 2024
In plain words
This statistical report shows how common brain and central nervous system tumours were in the United States in 2017 to 2021 and who was most often affected. About 73% of these tumours were non-cancerous (non-malignant), but glioblastoma was the most common cancerous (malignant) tumour. Five years after diagnosis, about 36% of patients with a malignant tumour and 92% of patients with a non-malignant tumour were alive. These figures are population averages, and each patient's outlook depends on the type of tumour and their own circumstances.
Key results
Study population
All primary malignant and non-malignant brain and other central nervous system (CNS) tumours diagnosed in the United States between 2017 and 2021. The CBTRUS registry, in collaboration with the Centers for Disease Control and Prevention (CDC) and the National Cancer Institute (NCI), covers the entire US population.
Endpoints
Average annual age-adjusted incidence rate (AAAIR) per 100,000 population (adjusted to the 2000 US standard population), histological distribution of tumours, mortality rates and five-year relative survival.
Safety and side effects
This is a registry-based statistical study with no therapeutic intervention or assessment of adverse events.
Clinical significance and place in guidelines
This report provides population-based reference data on the incidence, histological distribution, mortality and survival of brain tumours in the United States and is useful for health-system planning and research. The abstract does not comment on changes to treatment guidelines or approvals, as this is a descriptive study and its data relate to the US population.
Limitations
According to the abstract, this report is descriptive and based on a US population-based registry, and it cannot be generalised directly to other populations. Comparisons between groups are not causal. Other limitations are discussed in the full report.
This summary was prepared by the editorial team from the published paper; the original paper is the final reference. Read the original abstract on PubMed.