Trends in the Incidence of Stomach Cancer in Golestan Province, a High-risk Area in Northern Iran, 2004–2016
- Study type
- Observational study
- Study name
- GPCR
- Design
- Population-based cancer registry study (temporal and geographical trends in incidence) with Joinpoint regression analysis
- Sample size
- 2964 patients with stomach cancer
- Source
- Arch Iran Med · 2020
In plain words
This study shows that stomach cancer is common in Golestan Province, one of the high-risk areas of Iran, and is seen more often in men and in people living in villages. The rate of new cases in men and in rural areas has slowly fallen, but the total number of new patients has risen because the population has grown and become older. More research is needed to understand the exact causes of this cancer in the region.
Key results
Treatment arms and regimens
This study is observational and had no therapeutic intervention; all stomach cancer cases recorded in the GPCR from 2004 to 2016 were analysed.
Source of the regimen details: Abstract of the paper
Doses are given for the information of specialists, as in this study’s protocol, and are not a prescription. Every drug must be prescribed by the treating physician for the individual patient.
Study population
Patients with stomach cancer recorded in the Golestan Population-based Cancer Registry (GPCR) between 2004 and 2016.
Endpoints
Age-standardised incidence rates (ASR) per 100,000 person-years, average annual percent change (AAPC) by Joinpoint regression, and the contributions of population ageing, population size and risk to the overall change in incidence.
Safety and side effects
This is an observational cancer registry study, and treatment adverse effects were not assessed.
Clinical significance and place in guidelines
This is a descriptive study based on cancer registry data and does not recommend any specific treatment. The findings emphasise the high burden of stomach cancer in Golestan and the need for health planning, given the rising number of cases due to population growth and ageing. The higher incidence in the eastern areas can guide regional prioritisation. The status of screening or prevention recommendations in current guidelines should be checked separately.
Limitations
Based on the abstract, the study is descriptive and did not examine risk factors for this cancer in the population; the authors themselves stress the need for further studies to identify risk factors. Other limitations should be checked in the full text of the paper.
This summary was prepared by the editorial team from the published paper; the original paper is the final reference. Read the original abstract on PubMed.