Latest Cancer TreatmentsDr. Mohammadreza Dabiri
Dr. Mohammadreza Dabiriفارسی
Clinical tool

HCT-CI Comorbidity Index Before Stem Cell Transplantation

Risk of non-relapse mortality after transplant from comorbidities (Sorror)

Updated: 27 October 20261 min read1 reference

Comorbidity index for haematopoietic stem cell transplantation (Sorror).

This calculator needs JavaScript; the formula and its interpretation are in the text of this page.

An aid for clinicians; it does not replace clinical judgement, local protocols or the drug label. Double-check every result before prescribing.

Interpretation

In the original study, 2-year non-relapse mortality was about 14%, 21% and 41% for scores 0, 1–2 and 3 or more [1]. The index, with age (HCT-CI/age) and disease status, helps choose between myeloablative and reduced-intensity conditioning. Details in the transplant indications and conditioning lesson.

Use the definitions exactly

Each variable has a precise definition (e.g., lung function based on haemoglobin-corrected DLco); score from pre-transplant tests rather than clinical impression [1].

Related cancer types

LeukaemiaLymphomaMultiple myeloma

Treatment regimens (physicians)

R-CHOP regimen: dose, schedule and practical pointsPola-R-CHP in DLBCLABVD in Hodgkin lymphoma and AVD after a negative PETBV-AVD in advanced Hodgkin lymphomaBR regimen (bendamustine and rituximab)VRd and D-VRd regimens in myelomaDRd regimen (daratumumab, lenalidomide, dexamethasone) in myeloma7+3 regimen (AML induction) and high-dose cytarabineKRd regimen (carfilzomib, lenalidomide, dexamethasone) in myelomaAzacitidine with venetoclax in AMLTretinoin (ATRA) and arsenic trioxide in APLVenetoclax and obinutuzumab in CLL (the 12-month CLL14 regimen)

Physician tools and lessons

Cumulative Anthracycline Dose and Doxorubicin EquivalentsTumour Lysis Syndrome: Cairo-Bishop Criteria and PreventionKhorana Score (Cancer-Associated Thrombosis Risk)IPI, R-IPI, NCCN-IPI and CNS-IPI Calculator for DLBCLFollicular Lymphoma International Prognostic Index (FLIPI) CalculatorInternational Prognostic Score (IPS) for Advanced Hodgkin LymphomaMantle Cell Lymphoma International Prognostic Index (MIPI) CalculatorCLL-IPI Calculator (Chronic Lymphocytic Leukaemia Prognostic Index)ELTS and Sokal Score Calculator in Chronic Myeloid Leukaemia (CML)Myeloma Staging Calculator: ISS, R-ISS and R2-ISS

References

1 reference
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Numbers in the text, such as [1], refer to these sources. Sources with a “Study card” button are summarised in the site’s evidence library.

  1. 1
    Hematopoietic cell transplantation (HCT)-specific comorbidity index: a new tool for risk assessment before allogeneic HCTSorror ML, Maris MB, Storb R, et al · Blood · 2005;106:2912-9
    DOIPubMed Back to text: 1 2

This page is based on reputable scientific sources and was last updated on 27 October 2026. The content of this website is for educational and informational purposes only and does not replace consultation, diagnosis or treatment by a specialist physician. Consult your treating physician about any treatment decision.

Printed from the website; the full and up-to-date version: https://drdabiri.com/en/tools/hct-ci-calculator/

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