Latest Cancer TreatmentsDr. Mohammadreza Dabiri
Dr. Mohammadreza Dabiriفارسی
Clinical tool

IPSS-R Calculator for Myelodysplastic Syndromes (MDS)

Cytogenetics, blasts, haemoglobin, platelets and neutrophils

Updated: 27 October 20261 min read2 references

Revised International Prognostic Scoring System for myelodysplastic syndromes (IPSS-R). For IPSS-M (with gene mutations), use its official calculator.

Cytogenetic group
Bone marrow blasts
Haemoglobin (g/dL)
Platelets (×1000 per µL)
Absolute neutrophils (×1000 per µL)

This calculator needs JavaScript; the formula and its interpretation are in the text of this page.

An aid for clinicians; it does not replace clinical judgement, local protocols or the drug label. Double-check every result before prescribing.

IPSS-R and IPSS-M

IPSS-R weights five variables into five risk groups [1]. IPSS-M adds mutations in 31 genes and moves about half of patients into a different group [2]; if a molecular panel is available, use the official IPSS-M calculator. Treatment details in the MDS lesson.

Related cancer types

Leukaemia

Treatment regimens (physicians)

BR regimen (bendamustine and rituximab)7+3 regimen (AML induction) and high-dose cytarabineAzacitidine with venetoclax in AMLTretinoin (ATRA) and arsenic trioxide in APLVenetoclax and obinutuzumab in CLL (the 12-month CLL14 regimen)

Physician tools and lessons

Cumulative Anthracycline Dose and Doxorubicin EquivalentsTumour Lysis Syndrome: Cairo-Bishop Criteria and PreventionHCT-CI Comorbidity Index Before Stem Cell TransplantationCLL-IPI Calculator (Chronic Lymphocytic Leukaemia Prognostic Index)ELTS and Sokal Score Calculator in Chronic Myeloid Leukaemia (CML)ELN 2022 Genetic Risk Classification of AMLIndications for haematopoietic stem cell transplantation, donor selection and conditioningGraft-versus-host disease (GVHD): prophylaxis, grading and treatment10 cheap steps that save patients' livesAcute myeloid leukaemia (AML): 2022 classification, ELN genetic risk and treatment

References

2 references
Show all references, 1 with a study cardClose the reference list

Numbers in the text, such as [1], refer to these sources. Sources with a “Study card” button are summarised in the site’s evidence library.

  1. 1
    Revised international prognostic scoring system for myelodysplastic syndromesGreenberg PL, Tuechler H, Schanz J, et al · Blood · 2012;120:2454-65
    DOIPubMed Back to text
  2. 2
    Molecular International Prognostic Scoring System for Myelodysplastic SyndromesBernard E, Tuechler H, Greenberg PL, et al · NEJM Evid · 2022;1:EVIDoa2200008
    Study cardDOIPubMed Back to text

This page is based on reputable scientific sources and was last updated on 27 October 2026. The content of this website is for educational and informational purposes only and does not replace consultation, diagnosis or treatment by a specialist physician. Consult your treating physician about any treatment decision.

Printed from the website; the full and up-to-date version: https://drdabiri.com/en/tools/ipss-r-calculator/

Related pages

27 October 2026 IPI, R-IPI, NCCN-IPI and CNS-IPI Calculator for DLBCL Calculator for the IPI, R-IPI, NCCN-IPI and CNS-IPI in diffuse large B-cell lymphoma (DLBCL) in the rituximab era. 27 October 2026 Follicular Lymphoma International Prognostic Index (FLIPI) Calculator FLIPI calculator for prognosis in follicular lymphoma and what it means for treatment decisions. 27 October 2026 International Prognostic Score (IPS) for Advanced Hodgkin Lymphoma IPS (Hasenclever score) calculator for advanced Hodgkin lymphoma and its place in current treatment.